Here are the 12 worst side effects of Amlodipine (a common blood pressure and angina medication) that you should NEVER ignore — because they may indicate serious or potentially life-threatening complications:
⚠️ 1. Swelling in the Legs, Ankles, or Feet (Edema)
Amlodipine often causes fluid retention. While mild swelling is common, sudden or severe swelling can be dangerous and should be reported.
⚠️ 2. Rapid or Irregular Heartbeat (Palpitations)
This may signal worsening heart function or arrhythmia. Seek help if your heart feels like it’s pounding, fluttering, or skipping beats.
⚠️ 3. Severe Dizziness or Fainting
Can indicate dangerously low blood pressure (hypotension), especially when standing up suddenly. Not normal — don’t ignore it.
⚠️ 4. Chest Pain or Worsening Angina
Though used to treat chest pain, Amlodipine can paradoxically make angina worse, especially when first starting it or increasing the dose.
⚠️ 5. Shortness of Breath
This could be due to fluid buildup (heart failure) or an allergic reaction. If breathing becomes difficult, seek emergency help.
⚠️ 6. Liver Problems (Yellowing Skin or Eyes)
Jaundice may indicate liver dysfunction. Also watch for dark urine, pale stools, or right upper abdominal pain.
⚠️ 7. Severe Fatigue or Weakness
If your energy levels crash without explanation, it could be due to low blood pressure, heart issues, or liver effects.
⚠️ 8. Numbness or Tingling in Hands/Feet
Some people experience nerve-like symptoms that may interfere with movement or grip strength.
⚠️ 9. Persistent Nausea or Stomach Pain
Could be a sign of gastrointestinal irritation or liver stress.
⚠️ 10. Swelling of the Face, Lips, or Tongue (Allergic Reaction)
A medical emergency — could mean anaphylaxis. Seek help immediately if you have trouble breathing or swallowing.
⚠️ 11. Mood Changes or Depression
Although rare, some people report mental health changes including depression, irritability, or confusion.
⚠️ 12. Irregular Urination or Muscle Cramps
These may indicate electrolyte imbalances, especially when combined with diuretics or other heart medications.
🚨 When to Call Your Doctor Immediately:
If you experience severe chest pain, shortness of breath, facial swelling, jaundice, or fainting, stop taking Amlodipine and get emergency help right away.
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